anti- HIF1a antibody

Спецификация

Clonality	monoclonal
Host	Mouse
Specificity	Human
Tested Application	ELISA, IF, WB
Delivery Time	2 to 4 working days
Clone ID	5H12
Isotype	IgG1
Form	liquid
Purification	protein A+G purified
Purity	≥95% as determined by SDS-PAGE
Uniprot ID	Q16665
Gene ID
Calculated MW	120 kDa
Ссылка на страницу на сайте производителя	ссылка
Инструкция	PDF
Background	Under normal oxygen conditions, HIF1a is continuously produced and destroyed, in a process involving hydroxylation, interaction with von Hippel-Lindau (VHL) protein, polyubiquitylation and subsequent proteasomal degradation. Under hypoxic conditions, hydroxylation is impaired and HIF1a is stabilized. HIF1a localizes in cytoplasm in normoxia, but it can translocate into nuclear in response to hypoxia. The calculated molecular weight of HIF1a is 93 kDa, but the modified protein HIF1a is about 110-120kDa (PMID: 11698256, .PMID: 7539918).
Immunogen	hypoxia inducible factor 1, alpha subunit(basic helix-loop-helix transcription factor)
Synonyms	BHLHE78, MOP1, PASD8
Recommended dilution	WB: 1:1000-1:10000; IF: 1:50-1:200
Cobalt Chloride treated HeLa cells were subjected to SDS PAGE followed by western blot with FNab09940(HIF1a Antibody) at dilution of 1:5000

Информация для заказа

Область использования: Моноклональные антитела	Производство:	Fine Biotech
	Метод:	Антитела
	Объем:	100µg
	Кат. номер:	FNab09940
Цена (с НДС 20%):	по запросу	В корзину
Наименование: anti- HIF1a antibody. Примечание: