anti- MMP12 antibody

Спецификация

Clonality	polyclonal
Host	Rabbit
Specificity	Human, Mouse
Tested Application	ELISA, WB, IHC, IF
Delivery Time	2 to 4 working days
Isotype	IgG
Form	liquid
Purification	Immunogen affinity purified
Purity	≥95% as determined by SDS-PAGE
Uniprot ID	P39900
Gene ID
Calculated MW	54 kDa, 45 kDa
Ссылка на страницу на сайте производителя	ссылка
Инструкция	PDF
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Background	MMP12(Matrix metalloproteinase-12) is a 54 kDa proenzyme that is processed into a 45 kDa and then a 22 kDa active form(15723202). MMP9 and MMP12 promote intimal thickening by independent cleavage of N-cadherin, which elevates vascular smooth muscle cell proliferation via beta-catenin signalling. Its overexpression in myeloid lineage cells plays a key role in modulating myelopoiesis, immune suppression, and lung tumorigenesis(PMID: 21378275).
Immunogen	matrix metallopeptidase 12(macrophage elastase)
Synonyms	HME, Macrophage elastase, Macrophage metalloelastase, Matrix metalloproteinase 12, ME, MME, MMP 12, MMP12
Recommended dilution	WB: 1:500-1:1000; IHC: 1:20-1:200; IF: 1:10-1:100
Immunohistochemistry of paraffin-embedded human lung cancer tissue slide using FNab05234(MMP12 Antibody) at dilution of 1:50
mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab05234(MMP12 Antibody) at dilution of 1:600

Информация для заказа

Область использования: Поликлональные антитела	Производство:	Fine Biotech
	Метод:	Антитела
	Объем:	100µg
	Кат. номер:	FNab05234
Цена (с НДС 20%):	по запросу	В корзину
Наименование: anti- MMP12 antibody. Примечание: