anti- Caspase 8 antibody

Спецификация

Clonality	monoclonal
Host	Mouse
Specificity	Human
Tested Application	ELISA, IHC, WB,IF,IP
Delivery Time	2 to 4 working days
Clone ID	2C2
Isotype	IgG1
Form	liquid
Purification	Protein A+G purification
Purity	≥95% as determined by SDS-PAGE
Uniprot ID	Q14790
Calculated MW	50-55 kDa, 25-32 kDa
Ссылка на страницу на сайте производителя	ссылка
Инструкция	PDF
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Background	Caspase 8, also named as MCH5, MACH, FLICE, and CAP4, belongs to the peptidase C14A family. It may participate in the GZMB apoptotic pathways and functions as an upstream regulator in a-bisabolol-induced apoptosis. Caspase 8 catalyzes an essential intermediate step in the ubiquitination and proteasome-mediated degradation of IRF3(PMID:21816816). It may control diabetic embryopathy-associated apoptosis via Caspase 8 is expressed as nine isoforms by alternative splicing with the molecular mass from 26 kDa to 62 kDa. This antibody can recognize pro-and cleaved-caspase 8.
Immunogen	caspase 8, apoptosis-related cysteine peptidase
Synonyms	Apoptotic cysteine protease, Apoptotic protease Mch 5, Casp 8, CASP8, Caspase 8, Caspase 8/p18, Caspase8, FADD like ICE, FLICE, ICE like apoptotic protease 5, MACH, MCH5
Recommended dilution	WB: 1:500-1:5000; IP: 1:200-1:2000; IHC: 1:100-1:400; IF: 1:50-1:500
Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using FNab01294(Caspase 8 Antibody) at dilution of 1:200 heat mediated antigen retrieved with Tris-EDTA buffer(pH9).
HepG2 cells were subjected to SDS PAGE followed by western blot with FNab01294(CASP8 antibody) at dilution of 1:1000

Информация для заказа

Область использования: Моноклональные антитела	Производство:	Fine Biotech
	Метод:	Антитела
	Объем:	100µg
	Кат. номер:	FNab01294
Цена (с НДС 20%):	по запросу	В корзину
Наименование: anti- Caspase 8 antibody. Примечание: