Phospho-CCR5 (Ser349) Antibody

Спецификация

Объем	100 мкл
Синонимы	C-C CKR-5, CKR5, CHEMR13, CMKBR5, CCR-5
Клональность	Polyclonal Antibody
Организм	Human
uniprot	P51681
Иммуноген	Peptide sequence around phosphorylation site of Serine 349 (E-I-S(p)-V-G) derived from Human CCR5.
Источник	Rabbit
Видовая специфичность	Human
Применение	ELISA, WB,WB:1:500-1:1000
Примечание	<p>Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 R5 isolates.<br/><br/>Martin Oppermann, J. Biol. Chem., Mar 1999, 274: 8875.<br />Beatrix Pollok-Kopp, J. Biol. Chem., Jan 2003, 278: 2190 - 2198.<br />Ramtin Rahbar, J. Virol., Jul 2006, 80: 7245 - 7259.<br />H Olbrich, J. Leukoc. Biol., Mar 1999, 65: 281.<br /></p>
Клональность1	Polyclonal
Изотип	IgG
Коньюгат	Non-conjugated
Буффер	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Форма	liquid
Хранение	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Метод очистки	Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Абревеатура	Phospho-Ser349
Области исследований	Neuroscience,Cancer,Cardiovascular,Immunology,Microbiology,Signal transduction
Ссылка на страницу на сайте производителя	ссылка
Western blot analysis of extracts from A549 cells (Lane 2), using CCR5 (Phospho-Ser349) Antibody. The lane on the left is treated with antigen-specific peptide.

Информация для заказа

Область использования: Поликлональные антитела Cusabio	Производство:	Cusabio
	Метод:	Антитела
	Объем:	100 мкл
	Кат. номер:	CSB-PA942331
Цена (с НДС 20%):	по запросу	В корзину
Наименование: Phospho-CCR5 (Ser349) Antibody. Примечание: дополнительная информация (на английском языке).