TFAP2A AntibodyСпецификация| Объем | 100 мкл | | Синонимы | AP-2 transcription factor, AP2A, AP2TF, TFAP2, TFAP2A | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P05549 | | Иммуноген | Synthesized peptide derived from human AP-2. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB, IHC,WB:1:500-1:3000, IHC:1:50-1:100 | | Примечание | Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle. Together with the CITED2 coactivator, stimulates the PITX2 P1 promoter transcription activation. Associates with chromatin to the PITX2 P1 promoter region.<br/><br/>ShunJiang Yu, J. Biol. Chem., May 2003, 278: 19597 - 19602.<br/>TT Chen, Mol. Cell. Biol., Jun 1997, 17: 3056 - 3064.<br/>Oscar B. Goodman, J. Biol. Chem., Oct 1995, 270: 23768.<br/>Didier Jean, J. Biol. Chem., Jun 1998, 273: 16501 | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Epigenetics and Nuclear Signaling | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from COLO205 cells, using AP-2 antibody.
 | Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using AP-2 antibody.
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Наименование: TFAP2A Antibody.