Recombinant human Interstitial collagenase protein

Relevance: Cleaves collagens of types I, II, and III at one site in the helical domain. Also cleaves collagens of types VII and X. In case of HIV infection, interacts and cleaves the secreted viral Tat protein, leading to a decrease in neuronal Tat's mediated neurotoxicity.
Product Info:
Source:
Purity: 90%
Image:
Tested applications: SDS-PAGE, ELISA
Storage Buffer: 6M guanidine hydrochloride, 20mM Tris
Storage: Store at -20?, for extended storage, conserve at -20? or -80?.
Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.
AA sequence:
Referrences: [1] "Cloning and characterization of human tumor cell interstitial collagenase." Templeton N.S., Brown P.D., Levy A.T., Margulies I.M.K., Liotta L.A., Stetler-Stevenson W.G. Cancer Res. 50:5431-5437(1990) [PubMed: 2167156] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA], SUBCELLULAR LOCATION. [2] "Comparison of human stromelysin and collagenase by cloning and sequence analysis." Whitham S.E., Murphy G., Angel P., Rahmsdorf H.J., Smith B., Lyons A., Harris T.J.R., Reynolds J.J., Herrlich P., Docherty A.J.P. Biochem. J. 240:913-916(1986) [PubMed: 3030290] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. [3] "Human fibroblast collagenase. Complete primary structure and homology to an oncogene transformation-induced rat protein." Goldberg G.I., Wilhelm S.M., Kronberger A., Bauer E.A., Grant G.A., Eisen A.Z. J. Biol. Chem. 261:6600-6605(1986) [PubMed: 3009463] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Alias: Fibroblast collagenase,Matrix metalloproteinase-1,MMP-1.

Информация для заказа

Область использования: Рекомбинантные белки Cusabio	Производство:	Cusabio
	Метод:
	Объем:	1 мг
	Кат. номер:	CSB-RP070074h
Цена (с НДС 20%):	по запросу	В корзину
Наименование: Recombinant human Interstitial collagenase protein. Примечание: дополнительная информация (на английском языке).