Recombinant human Interferon-induced transmembrane protein 1 protein

Relevance: IFN-induced antiviral protein that mediate cellular innate immunity to at least three major human pathogens, namely influenza A H1N1 virus, West Nile virus, and dengue virus by inhibiting the early step(s) of replication. Plays a key role in the antiproliferative action of IFN-gamma either by inhibiting the ERK activition or by arresting cell growth in G1 phase in a p53-dependent manner. Implicated in the control of cell growth. Component of a multimeric complex involved in the transduction of antiproliferative and homotypic adhesion signals.
Product Info: GST-tagged
Source: E.coli derived
Purity: 95%
Image:
Tested applications: SDS-PAGE, ELISA, Western blot
Storage Buffer: PBS buffer,20mM GSH
Storage: Store at -20?, for extended storage, conserve at -20? or -80?.
Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.
AA sequence: MHKEEHEVAVLGAPPSTILPRSTVINIHSETSVPDH
Referrences: [1] "A single DNA response element can confer inducibility by both alpha- and gamma-interferons." Reid L.E., Brasnett A.H., Gilbert C.S., Porter A.C.G., Gewert D.R., Stark G.R., Kerr I.M. Proc. Natl. Acad. Sci. U.S.A. 86:840-844(1989) [PubMed: 2492664] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA], VARIANT ALA-13. [2] "Expression cloning of an interferon-inducible 17-kDa membrane protein implicated in the control of cell growth." Deblandre G.A., Marinx O.P., Evans S.S., Majjaj S., Leo O., Caput D., Huez G.A., Wathelet M.G. J. Biol. Chem. 270:23860-23866(1995) [PubMed: 7559564] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA], VARIANT ALA-13. [3] "Human chromosome 11 DNA sequence and analysis including novel gene identification." Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K., Lloyd C., Itoh T., Takeda T., Kim D.-W., She X., Barlow K.F., Bloom T., Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G. , Jaffe D.B., LaButti K., Nicol R., Park H.-S., Seaman C., Sougnez C., Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A., Hattori M., Rogers J., Lander E.S., Sakaki Y. Nature 440:497-500(2006) [PubMed: 16554811] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. [4] "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANT ALA-13. Tissue: Cervix.
Alias: Interferon-induced protein 17,Interferon-inducible protein 9-27,Leu-13 antigen,CD_antigen=CD225.

Информация для заказа

Область использования: Рекомбинантные белки Cusabio	Производство:	Cusabio
	Метод:
	Объем:	10 мкг
	Кат. номер:	CSB-RP012044h
Цена (с НДС 20%):	по запросу	В корзину
Наименование: Recombinant human Interferon-induced transmembrane protein 1 protein. Примечание: дополнительная информация (на английском языке).