Объем | 100 мкл |
Синонимы | BCL2-antagonist/killer 1 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q16611 |
Иммуноген | Fusion protein of human BAK1 |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA, WB, IHC,ELISA:1:2000-1:5000, WB:1:1000-1:5000, IHC:1:50-1:200 |
Примечание | The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antigen affinity purification |
Области исследований | Cell biology |
Ссылка на страницу на сайте производителя | ссылка |
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA089402(BAK1 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ?200)
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The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA089402(BAK1 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ?200)
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Gel: 12%SDS-PAGE, Lysate: 40 ?g, Lane 1-4: Hela cells, A431 cells, 293T cells, Jurkat cells, Primary antibody: CSB-PA089402(BAK1 Antibody) at dilution 1/900, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 seconds
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