| Clonality | polyclonal |
| Host | Rabbit |
| Specificity | Human, Mouse, Rat |
| Tested Application | ELISA, WB, IHC |
| Delivery Time | 2 to 4 working days |
| Isotype | IgG |
| Form | liquid |
| Purification | Immunogen affinity purified |
| Purity | ≥95% as determined by SDS-PAGE |
| Uniprot ID | Q9BRG1 |
| Gene ID | |
| Calculated MW | 28 kDa |
| Ссылка на страницу на сайте производителя | ссылка |
| Инструкция | PDF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| Background | Component of the ESCRT-II complex(endosomal sorting complex required for transport II), which is required for multivesicular body(MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. The ESCRT-II complex may also play a role in transcription regulation, possibly via its interaction with ELL. The ESCRT-II complex may be involved in facilitating the budding of certain RNA viruses. |
| Immunogen | vacuolar protein sorting 25 homolog(S. cerevisiae) |
| Synonyms | DERP9, EAP20, ESCRT II complex subunit VPS25, FAP20, hVps25, VPS25 |
| Recommended dilution | WB: 1:500-1:5000; IHC: 1:20-1:200 |
Immunohistochemistry of paraffin-embedded human breast cancer using FNab09431(VPS25 antibody) at dilution of 1:50
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HeLa cells were subjected to SDS PAGE followed by western blot with FNab09431(VPS25 antibody) at dilution of 1:500
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