anti- VHL antibody

Clonality	polyclonal
Host	Rabbit
Specificity	Human, Mouse, Rat
Tested Application	ELISA, IF, IHC
Delivery Time	2 to 4 working days
Isotype	IgG
Form	liquid
Purification	Immunogen affinity purified
Purity	≥95% as determined by SDS-PAGE
Uniprot ID	P40337
Gene ID
Calculated MW	64 kDa
Ссылка на страницу на сайте производителя	ссылка
Инструкция	PDF
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Background	Involved in the ubiquitination and subsequent proteasomal degradation via the von Hippel-Lindau ubiquitination complex. Seems to act as a target recruitment subunit in the E3 ubiquitin ligase complex and recruits hydroxylated hypoxia-inducible factor(HIF) under normoxic conditions. Involved in transcriptional repression through interaction with HIF1A, HIF1AN and histone deacetylases. Ubiquitinates, in an oxygen-responsive manner, ADRB2.
Immunogen	von Hippel-Lindau tumor suppressor
Synonyms	HRCA1, Protein G7, pVHL, RCA1, VHL, VHL1, Von Hippe-Lindau
Recommended dilution	IF: 1:10-1:100; IHC: 1:20-1:200
Immunohistochemical of paraffin-embedded human kidney using FNab09402(VHL antibody) at dilution of 1:50

Область использования: Поликлональные антитела	Производство:	Fine Biotech
	Метод:	Антитела
	Объем:	100µg
	Кат. номер:	FNab09402
Цена (с НДС 20%):	по запросу	В корзину
Наименование: anti- VHL antibody. Примечание: