| Clonality | polyclonal |
| Host | Rabbit |
| Specificity | Human |
| Tested Application | ELISA, WB, IHC |
| Delivery Time | 2 to 4 working days |
| Isotype | IgG |
| Form | liquid |
| Purification | Immunogen affinity purified |
| Purity | ≥95% as determined by SDS-PAGE |
| Uniprot ID | Q9UK80 |
| Gene ID | |
| Calculated MW | 110 kDa |
| Ссылка на страницу на сайте производителя | ссылка |
| Инструкция | PDF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| Background | Deubiquitinates histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A releaves the repression of di-and trimethylation of histone H3 at 'Lys-4', resulting in regulation of transcriptional initiation. Regulates gene expression via histone H2A deubiquitination(By similarity). Also capable of removing NEDD8 from NEDD8 conjugates but has no effect on Sentrin-1 conjugates(PubMed:10799498). Deubiquitinates BAZ2A/TIP5 leading to its stabilization(PubMed:26100909). |
| Immunogen | ubiquitin specific peptidase 21 |
| Synonyms | Deubiquitinating enzyme 21, Ubiquitin thiolesterase 21, USP16, USP21, USP23 |
| Recommended dilution | WB: 1:200-1:2000; IHC: 1:20-1:200 |
Immunohistochemistry of paraffin-embedded human heart tissue slide using FNab09318(USP21 Antibody) at dilution of 1:50
 |
RAW 264.7 cells were subjected to SDS PAGE followed by western blot with FNab09318(USP21 Antibody) at dilution of 1:600
 |
| | |
