| Объем | 100 мкл |
| Синонимы | Transcription factor 7-like 1, HMG box transcription factor 3, TCF-3, TCF7L1, TCF3 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q9HCS4 |
| Иммуноген | Synthesized peptide derived from internal of human TCF7L1. |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, WB,WB:1:500-1:3000 |
| Примечание | Participates in the Wnt signaling pathway. Binds to DNA and acts as a repressor in the absence of CTNNB1, and as an activator in its presence. Necessary for the terminal differentiation of epidermal cells, the formation of keratohyalin granules and the development of the barrier function of the epidermis By similarity. Down-regulates NQO1, leading to increased mitomycin c resistance.<br/><br/>Sagara N., Cancer Res. 60:5959-5962(2000).<br/>Hillier L.W., Nature 434:724-731(2005).<br/>Castrop J., Nucleic Acids Res. 20:611-611(1992).<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Epigenetics and Nuclear Signaling,Stem cells |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from 3T3 cells, using TCF7L1 antibody.
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Наименование: TCF7L1 Antibody.