AOX1 AntibodyСпецификация| Объем | 100 мкл | | Синонимы | Aldehyde oxidase, EC 1.2.3.1, | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q06278 | | Иммуноген | Synthesized peptide derived from internal of human AOX1. | | Источник | Rabbit | | Видовая специфичность | Human | | Применение | ELISA, WB, IHC,WB:1:500-1:3000, IHC:1:50-1:100 | | Примечание | Oxidase with broad substrate specificity, oxidizing aromatic azaheterocycles, such as N1-methylnicotinamide and N-methylphthalazinium, as well as aldehydes, such as benzaldehyde, retinal, pyridoxal, and vanillin. Plays a key role in the metabolism of xenobiotics and drugs containing aromatic azaheterocyclic substituents. Participates in the bioactivation of prodrugs such as famciclovir, catalyzing the oxidation step from 6-deoxypenciclovir to penciclovir, which is a potent antiviral agent. Is probably involved in the regulation of reactive oxygen species homeostasis. May be a prominent source of superoxide generation via the one-electron reduction of molecular oxygen. Also may catalyze nitric oxide (NO) production via the reduction of nitrite to NO with NADH or aldehyde as electron donor. May play a role in adipogenesis.<br/><br/>Wright R.M., Proc. Natl. Acad. Sci. U.S.A. 90:10690-10694(1993).<br/>Wright R.M., Redox Rep. 3:135-144(1997).<br/>Hillier L.W., Nature 434:724-731(2005).<br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Cancer,Metabolism,Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from HeLa cells, using AOX1 antibody.
 | Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using AOX1 antibody.
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Наименование: AOX1 Antibody.