DCC AntibodyСпецификация| Объем | 100 мкл | | Синонимы | colorectal cancer suppressor, deleted in colorectal carcinoma, netrin receptor DCC, tumor suppressor protein DCC, | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P43146 | | Иммуноген | Synthesized peptide derived from internal of human DCC. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse | | Применение | ELISA, IF,IF:1:100-1:500 | | Примечание | Receptor for netrin required for axon guidance. Mediates axon attraction of neuronal growth cones in the developing nervous system upon ligand binding. Its association with UNC5 proteins may trigger signaling for axon repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. Implicated as a tumor suppressor gene.<br/><br/>Hedrick L., Genes Dev. 8:1174-1183(1994).<br/>Cho K.R., Genomics 19:525-531(1994).<br/>Sjoeblom T., Science 314:268-274(2006). | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Epigenetics and Nuclear Signaling,Neuroscience,Cancer,Cell biology | | Ссылка на страницу на сайте производителя | ссылка | Immunofluorescence analysis of LOVO cells, using DCC antibody.
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Наименование: DCC Antibody.