CFL1/CFL2 AntibodyСпецификация| Объем | 100 мкл | | Синонимы | CFL2, COF2, Cofilin 2, Cofilin, muscle isoform | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P23528/Q9Y281 | | Иммуноген | Synthesized peptide derived from internal of human Cofilin. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB,WB:1:500-1:3000 | | Примечание | Binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity. Regulates actin cytoskeleton dynamics. Important for normal progress through mitosis and normal cytokinesis. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required for the up-regulation of atypical chemokine receptor ACKR2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation.<br/><br/>Thirion C., Eur. J. Biochem. 268:3473-3482(2001).<br/>Zhang Y., Mol. Cell. Proteomics 4:1240-1250(2005).<br/>Olsen J.V., Cell 127:635-648(2006).<br/><br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Neuroscience,Cancer,Cardiovascular,Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from Jurkat cells and HeLa cells, using Cofilin antibody.
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Наименование: CFL1/CFL2 Antibody.