ADIPOQ AntibodyСпецификация| Объем | 100 мкл | | Синонимы | ACDC, ADPN, APM1 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q15848 | | Иммуноген | Peptide sequence around aa.235~239(T-G-F-L-L) derived from Human Adiponectin. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB,WB:1:500-1:1000 | | Примечание | Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-a by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.<br/><br/>Yamauchi T., Kamon J., Waki H. Kadowaki T.Nat. Med. 7:941-946(2001)<br/>Richards A.A., Stephens T., Charlton H.K. Mol. Endocrinol. 20:1673-1687(2006) | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. | | Области исследований | Neuroscience,Cancer,Cardiovascular,Metabolism,Signal transduction,Stem cells | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from Rat and Mouse brain tissue using Adiponectin Antibody.
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Наименование: ADIPOQ Antibody.