ABCG2 AntibodyСпецификация| Объем | 100 мкл | | Синонимы | BMDP, MRX, ABC15, ABCP, BCRP1 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q9UNQ0 | | Иммуноген | Peptide sequence around aa.160~164( R-I-N-R-V) derived from Human ABCG2(CD338). | | Источник | Rabbit | | Видовая специфичность | Human | | Применение | ELISA, WB,WB:1:500-1:1000 | | Примечание | <p>Xenobiotic transporter that may play an important role in the exclusion of xenobiotics from the brain. May be involved in brain-to-blood efflux. Appears to play a major role in the multidrug resistance phenotype of several cancer cell lines. When overexpressed, the transfected cells become resistant to mitoxantrone, daunorubicin and doxorubicin, display diminished intracellular accumulation of daunorubicin, and manifest an ATP-dependent increase in the efflux of rhodamine 123. <br /><br />Henriksen U., Gether U., Litman T.J. Cell Sci. 118:1417-1426(2005) Wakabayashi K., Nakagawa H., Tamura A., Koshiba S., Hoshijima K., Komada M., Ishikawa T. J. Biol. Chem. 282:27841-27846(2007)</p> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. | | Области исследований | Cancer,Tags & Cell Markers,Metabolism,Signal transduction,Stem cells | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extract from HL-60 cells using ABCG2(CD338) Antibody
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Наименование: ABCG2 Antibody.