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/ Каталог / Производители лабораторного оборудования, реагентов и расходных материалов / OriGene

Carbonic Anhydrase IX (CA9) (NM_001216) Human Tagged ORF Clone


Product Data
Product Name Carbonic Anhydrase IX (CA9) (NM_001216) Human Tagged ORF Clone
Type Human Tagged ORF Clone
Tag TurboGFP
Symbol CA9
Synonyms CAIX; MN
Vector pCMV6-AC-GFP
E. coli Selection Ampicillin (100 ug/mL)
Cell Selection Neomycin
Sequence Data
Restriction Sites SgfI-MluI      Cloning Scheme for this gene     Plasmid Map     
Tag TurboGFP
ACCN NM_001216
ORF Size 1377 bp
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Product Components The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Reference Data
RefSeq NM_001216.1, NP_001207.1
RefSeq Size 1552
RefSeq ORF 1380
Locus ID 768
Cytogenetics 9p13.3
Protein Families Druggable Genome, Transmembrane
Protein Pathways Nitrogen metabolism
Gene Summary Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and is one of only two tumor-associated carbonic anhydrase isoenzymes known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. This gene was mapped to 17q21.2 by fluorescence in situ hybridization, however, radiation hybrid mapping localized it to 9p13-p12. [provided by RefSeq, Jun 2014]

Информация для заказа

Область использования:Производство:OriGene
Объем:10 ug 
Кат. номер:RG204839
Цена (с НДС 20%):по запросуВ корзину
Наименование: Carbonic Anhydrase IX (CA9) (NM_001216) Human Tagged ORF Clone.
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info@LD.ru   тел.: +7 495 369-20-43