Product Type: Native protein
Availability: one week
Source: Purified from human milk
Peptide: Full length native Human lactoferrin
Relevance: Lactoferrin is a glycoprotein present in most human mucosal secretions, including human milk. Lactoferrin is bacteriostatic in low iron media and, in some settings, bactericidal. Lactoferrin impairs ability of Shigella flexneri serotype 5 strain M90T to invade HeLa cells. To determine the mechanism by which lactoferrin decreases invasiveness of Shigella organisms, its effect on the major virulence proteins responsible for bacterial uptake by host cells was evaluated. Lactoferrin induced degradation of invasion plasmid antigens IpaB and, to a lesser extent, IpaC, the key proteins responsible for bacteria-directed phagocytosis by mammalian cells.
Storage Buffer: Tris pH8.0
Stability & Storage : Aliquot and store at -20? or -80?. Avoid repeated freeze / thaw cycles
Информация для заказа