Recombinant human Substance-P receptor protein

Relevance: This is a receptor for the tachykinin neuropeptide substance P. It is probably associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance P > substance K > neuromedin-K.
Product Info: GST tagged
Source: E.coli derived
Purity: 90%
Image:
Tested applications: SDS-PAGE, ELISA
Storage Buffer: PBS buffer, 20mM GSH
Storage: Store at -20?, for extended storage, conserve at -20? or -80?.
Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.
AA sequence: MDNVLPVDSDLSPNISTNTSEPNQFVQPA
Referrences: [1] "Molecular cloning, structural characterization and functional expression of the human substance P receptor." Takeda Y., Chou K.B., Takeda J., Sachais B.S., Krause J.E. Biochem. Biophys. Res. Commun. 179:1232-1240(1991) [PubMed: 1718267] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. [2] "Isolation and characterisation of the human lung NK-1 receptor cDNA." Hopkins B., Powell S.J., Danks P., Briggs I., Graham A. Biochem. Biophys. Res. Commun. 180:1110-1117(1991) [PubMed: 1659396] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Tissue: Lung. [3] "Human substance P receptor (NK-1): organization of the gene, chromosome localization, and functional expression of cDNA clones." Gerard N.P., Garraway L.A., Eddy R.L. Jr., Shows T.B., Iijima H., Paquet J.L., Gerard C. Biochemistry 30:10640-10646(1991) [PubMed: 1657150] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Alias: NK-1 receptor Short name=NK-1R Tachykinin receptor 1.

Информация для заказа

Область использования: Рекомбинантные белки Cusabio	Производство:	Cusabio
	Метод:
	Объем:	500 мкг
	Кат. номер:	CSB-RP096744h
Цена (с НДС 20%):	по запросу	В корзину
Наименование: Recombinant human Substance-P receptor protein. Примечание: дополнительная информация (на английском языке).