Recombinant human SPARC protein

Relevance: Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca2+ with a low affinity and an EF-hand loop that binds a Ca2+ ion with a high affinity.
Product Info:
Source:
Purity: 90%
Image:
Tested applications: SDS-PAGE, ELISA
Storage Buffer: PBS buffer, 20mM GSH
Storage: Store at -20?, for extended storage, conserve at -20? or -80?.
Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.
AA sequence:
Referrences: [1] "Cloning and complete amino acid sequences of human and murine basement membrane protein BM-40 (SPARC, osteonectin)." Lankat-Buttgereit B., Mann K., Deutzmann R., Timpl R., Krieg T. FEBS Lett. 236:352-356(1988) [PubMed: 3410046] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA], PARTIAL PROTEIN SEQUENCE. Tissue: Placenta. [2] "Molecular analysis of the cDNA for human SPARC/osteonectin/BM-40: sequence, expression, and localization of the gene to chromosome 5q31-q33." Swaroop A., Hogan B.L.M., Francke U. Genomics 2:37-47(1988) [PubMed: 2838412] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. [3] "Structure of human osteonectin based upon analysis of cDNA and genomic sequences." Villarreal X.C., Mann K.G., Long G.L. Biochemistry 28:6483-6491(1989) [PubMed: 2790009] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Alias: Basement-membrane protein 40,BM-40,Osteonectin,ON,Secreted protein acidic and rich in cysteine.

Информация для заказа

Область использования: Рекомбинантные белки Cusabio	Производство:	Cusabio
	Метод:
	Объем:	200 мкг
	Кат. номер:	CSB-RP094444h
Цена (с НДС 20%):	по запросу	В корзину
Наименование: Recombinant human SPARC protein. Примечание: дополнительная информация (на английском языке).