ООО «Лабораторная Диагностика»
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/ Каталог / Протеомика / Белки / Рекомбинантные белки / Рекомбинантные белки ProSpec, Panomics и Евроген / Цитокины

Recombinant Human Interleukin 4, HEK


Synonyms BCGF, BCDF, B cell stimulating factor, BSF-1, Lymphocyte stimulatory factor 1, IL-4, MGC79402, Binetrakin, Pitrakinra.
Introduction IL4 is a pleiotropic cytokine produced by activated T cells. IL4 is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. IL4, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Description IL-4 Human Recombinant produced in HEK cells is a glycosylated monomer, having a molecular weight range of 14-19kDa due to glycosylation.
The IL-4 is purified by proprietary chromatographic techniques.
Source HEK.
Physical Appearence Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation The IL4 was lyophilized from 1mg/ml in 1xPBS.
Solubility It is recommended to reconstitute the lyophilized IL-4 in sterile water not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
Stability Lyophilized IL-4 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IL4 should be stored at 4°C between 2-7 days and for future use below -18°C.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please prevent freeze-thaw cycles.
Purity Greater than 95% as obsereved by SDS-PAGE.
Biological Activity The activity was determined by the dose dependent stimulation of the proliferation of human TF-1 cells (human erythroleukemic indicator cell line) and is typically 0.1-0.5ng/ml.
Usage ProSpecs products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Информация для заказа

Область использования:Производство:ProSpec
Объем:1 мг 
Кат. номер:cyt-097
Цена (с НДС 20%):по запросуВ корзину
Recombinant Human Interleukin 4, HEK / IL 4 HEKНаименование: Recombinant Human Interleukin 4, HEK / IL 4 HEK.
Примечание: см. также другие объемы фасовки.
Дополнительная информация (на сайте www.prospecbio.com)
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info@LD.ru   тел.: +7 495 369-20-43