Phospho-XIAP (Ser87) Antibody

Спецификация

Объем	100 мкл
Синонимы	API3, BIR4, BIRC4, IAP3, X-linked IAP
Клональность	Polyclonal Antibody
Организм	Human
uniprot	P98170
Иммуноген	Peptide sequence around phosphorylation site of serine87(K-V-S(p)-P-N) derived from Human XIAP .
Источник	Rabbit
Видовая специфичность	Human, Mouse, Rat
Применение	ELISA, WB,WB:1:500-1:1000
Примечание	<p>Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, copper homeostasis, mitogenic kinase signaling, cell proliferation, as well as cell invasion and metastasis. Acts as a direct caspase inhibitor. Directly bind to the active site pocket of CASP3 and CASP7 and obstructs substrate entry. Inactivates CASP9 by keeping it in a monomeric, inactive state. <br/><br/>Huang X, Wu Z, Mei Y, Wu M (2013)EMBO J 32, 2204-16. Bornhauser BC, et al. (2007) Blood 110, 2084-91.Dan HC, et al. (2004)J Biol Chem 279, 5405-12.</p>
Клональность1	Polyclonal
Изотип	IgG
Коньюгат	Non-conjugated
Буффер	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Форма	liquid
Хранение	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Метод очистки	Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Абревеатура	Phospho-Ser87
Области исследований	Cancer,Cell biology,Metabolism
Ссылка на страницу на сайте производителя	ссылка
Western blot analysis of extracts from HepG2 cells treated with Anisomycin using Phospho-XIAP (Ser87) antibody.The lane on the right is treated with the antigen-specific peptide.

Информация для заказа

Область использования: Антитела XIAP Поликлональные антитела Cusabio	Производство:	Cusabio
	Метод:	Антитела
	Объем:	100 мкл
	Кат. номер:	CSB-PA548634
Цена (с НДС 20%):	по запросу	В корзину
Наименование: Phospho-XIAP (Ser87) Antibody. Примечание: дополнительная информация (на английском языке).