| Объем | 100 мкл |
| Синонимы | JAK-2, JAK2, Janus kinase 2, kinase Jak2, |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | O60674 |
| Иммуноген | Peptide sequence around phosphorylation site of tyrosine 1007 (K-E-Y(p)-Y-K) derived from Human JAK2. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse, Rat |
| Применение | ELISA, WB, IHC,WB:1:500-1:1000, IHC:1:50-1:100 |
| Примечание | Plays a role in leptin signaling and control of body weight<br/><br/>James C, et al. (2005) Nature. 434(7037): 1144-1148.<br/>Argetsinger LS, et al. (2004) Mol Cell Biol. 24(11): 4955-4967.<br/>Ungureanu D, et al. (2002) Mol Cell Biol. 22(10): 3316-3326.<br/>Xie S, et al. (2001) Oncogene. 20(43): 6188-6195. <br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Абревеатура | Phospho-Tyr1007 |
| Области исследований | Epigenetics and Nuclear Signaling,Cancer,Cell biology,Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from HT29 cells untreated or treated with IL-4 using JAK2(Phospho-Tyr1007) Antibody.
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Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using JAK2(Phospho-Tyr1007) Antibody(left) or the same antibody preincubated with blocking peptide(right).
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Наименование: Phospho-JAK2 (Tyr1007) Antibody.