| Объем | 100 мкл |
| Синонимы | FLJ40509, I-kappa-B kinase, IKBKB, kinase beta, NFKBIKB |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | O15111/O14920 |
| Иммуноген | Peptide sequence around phosphorylation site of serine 180/181 (C-T-S(p)-F-V) derived from Human IKK- alpha/ beta. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse, Rat |
| Применение | ELISA, WB,WB:1:500-1:1000 |
| Примечание | <p>Acts as part of the IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Also phosphorylates NCOA3.<br/><br/>Hafeez BB, et al. (2008) Cancer Res 68, 8564-72 <br />Cahill CM, Rogers JT (2008) J Biol Chem 283, 25900-12 <br />Encinas M, et al. (2008)Cell Death Differ 15, 1510-21</p> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Абревеатура | Phospho-Ser180/181 |
| Области исследований | Cancer,Cardiovascular,Cell biology,Immunology,Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from HepG2 cells treated with TNF using IKK- alpha/ beta (Phospho-Ser180/181) antibody.The lane on the right is treated with the antigen-specific peptide.
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Наименование: Phospho-CHUK/IKBKB (Ser180/181) Antibody.