FAS AntibodyСпецификация| Объем | 100 мкл | | Синонимы | Apo-1, CD95, FasL receptor, TNFRSF6, TNR6 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P25445 | | Иммуноген | Synthesized peptide derived from C-terminal of human Fas. | | Источник | Rabbit | | Видовая специфичность | Human | | Применение | ELISA, WB, IHC,WB:1:500-1:3000, IHC:1:50-1:100 | | Примечание | Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).<br/><br/>Michael J. Pinkoski, Am JPhysiol Gastrointest Liver Physiol, Mar 2000, 278: 354. <br/>Morgan Jenkins, J. Immunol., Aug 1999, 163: 1195. <br/>Nicholas Mitsiades, J Natl Cancer Inst, Oct 1999, 91: 1678 - 1684. <br/>JOS E. CARDIER, FASEB J, Nov 1999, 13: 1950.<br/> <br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Cell biology,Immunology | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from LOVO cells, using Fas antibody.
 | Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using Fas antibody.
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Наименование: FAS Antibody.