| Объем | 100 мкл |
| Синонимы | BCL2 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P10415 |
| Иммуноген | Peptide sequence around aa. 54~58 (G-H-T-P-H) derived from Human BCL-2. |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, WB, IHC, IF,WB:1:500-1:1000, IHC:1:50-1:200, IF:1:100-1:200 |
| Примечание | Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).<br/><br/>Ling, Y. H. et al. (1998) J. Biol. Chem. 273, 18984-18991.<br/>Huang, S.J. and Cidlowski, J.A. (2002) FASEB 16, 825-832.<br/>Deng, X. et al. (2001) J. Biol. Chem. 276, 23681-23688.<br/>Huang ST,et al. (2002) FASEB J Jun, 16(8): 825-32.<br/>Yamamoto, K. et al. (1999) Mol. Cell. Biol. 19, 8469-8478.<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. |
| Области исследований | Cancer,Cell biology,Metabolism,Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from Hela, A2780 and 293 cells using BCL-2(Ab-56) Antibody.
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Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using BCL-2(Ab-56) Antibody(left) or the same antibody preincubated with blocking peptide(right).
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Immunofluorescence staining of methanol-fixed Hela cells using BCL-2(Ab-56) Antibody.
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Наименование: BCL2 (Ab-56) Antibody.