Антитела поликлональные кроличьи к Occludin (H-279)Occludin Antibody (H-279) is a rabbit polyclonal IgG
- Occludin Antibody (H-279) is a rabbit polyclonal IgG provided at 200 µg/ml
- epitope corresponding to amino acids 132-411 mapping within an internal region of Occludin of human origin
- recommended for detection of Occludin of mouse, rat, human and canine origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, bovine and porcine
- See 20 citations for Occludin Antibody (H-279)
Occludin is an integral membrane protein closely associated with the tight junctions of epithelial and endothelial cells. Occludin is a tetraspan integral membrane protein in epithelial and endothelial tight junction (TJ) structures that can contain two extracellular loops. The protein exists in a variety of phosphorylated forms. Phosphorylation is involved in regulating both the localization and the function of occludin. Expression of occludin is up-regulated by poly-unsaturated fatty acids, increasing transendothelial cell resistance and reducing cellular permeability to large molecules. The level of occludin varies greatly depending on tissue; in brain tissue, occludin is highly expressed at cell-cell contact sites. Non-neural tissues show lower expression and discontinuous distribution. Up-regulation of epithelial occludin may play a role in enhancing paracellular permeability and be related to the damage to the tight junction. Информация для заказа| Область использования: | Производство: | Santa Cruz | | Метод: | | | Объем: | 200 мкг/мл | | Кат. номер: | sc-5562 | | Цена (с НДС 20%): | по запросу | В корзину  |  Наименование: Антитела поликлональные кроличьи к Occludin (H-279) / Occludin Antibody (H-279) is a rabbit polyclonal IgG.
Примечание: SQ Category: Primary Antibodies,
Species: m, r, h,
Host Origin: human,
Applications: WB, IP, IF, ELISA,
UNSPSC: 12352203,
datasheet |
|
