| Clonality | polyclonal |
| Host | Rabbit |
| Specificity | Human |
| Tested Application | ELISA, WB, IHC |
| Delivery Time | 2 to 4 working days |
| Isotype | IgG |
| Form | liquid |
| Purification | Immunogen affinity purified |
| Purity | ≥95% as determined by SDS-PAGE |
| Uniprot ID | Q96K21 |
| Gene ID | |
| Calculated MW | 52 kDa |
| Ссылка на страницу на сайте производителя | ссылка |
| Инструкция | PDF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| Background | Key regulator of abscission step in cytokinesis: part of the cytokinesis checkpoint, a process required to delay abscission to prevent both premature resolution of intercellular chromosome bridges and accumulation of DNA damage. Together with CHMP4C, required to retain abscission-competent VPS4(VPS4A and/or VPS4B) at the midbody ring until abscission checkpoint signaling is terminated at late cytokinesis. Deactivation of AURKB results in dephosphorylation of CHMP4C followed by its dissociation from ZFYVE19/ANCHR and VPS4 and subsequent abscission. |
| Immunogen | zinc finger, FYVE domain containing 19 |
| Synonyms | FLJ14840, MPFYVE, ZFYVE19 |
| Recommended dilution | WB: 1:1000-1:10000; IHC: 1:20-1:200 |
Immunohistochemistry of paraffin-embedded human heart slide using FNab09629(ZFYVE19 Antibody) at dilution of 1:50
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HeLa cells were subjected to SDS PAGE followed by western blot with FNab09629(ZFYVE19 antibody) at dilution of 1:2000
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