| Clonality | monoclonal |
| Host | Mouse |
| Specificity | Human, Mouse, Rat |
| Tested Application | ELISA, WB, IHC |
| Delivery Time | 2 to 4 working days |
| Clone ID | 4G6 |
| Isotype | IgG2a |
| Form | liquid |
| Purification | Protein A+G purification |
| Purity | ≥95% as determined by SDS-PAGE |
| Uniprot ID | Q13586 |
| Gene ID | |
| Calculated MW | 77kd |
| Ссылка на страницу на сайте производителя | ссылка |
| Инструкция | PDF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| Background | Plays a role in mediating store-operated Ca(2+) entry(SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores(By similarity). Acts as Ca(2+) sensor in the endoplasmic reticulum via its EF-hand domain. Upon Ca(2+) depletion, translocates from the endoplasmic reticulum to the plasma membrane where it activates the Ca(2+) release-activated Ca(2+)(CRAC) channel subunit ORAI1(PubMed:16208375). Involved in enamel formation(By similarity). Activated following interaction with TMEM110/STIMATE, leading to promote STIM1 conformational switch(By similarity). |
| Immunogen | stromal interaction molecule 1 |
| Synonyms | D11S4896E, GOK, STIM1, stromal interaction molecule 1 |
| Recommended dilution | WB: 1:200-1:2000
IHC: 1:50-1:500 |
Immunohistochemistry of paraffin-embedded human lung cancer tissue slide using FNab08321(STIM1 Antibody) at dilution of 1:200(under 10x lens). heat mediated antigen retrieved with Tris-EDTA buffer(pH9).
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Jurkat cells were subjected to SDS PAGE followed by western blot with FNab08321(STIM1 Antibody) at dilution of 1:500
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