anti- PARP1 antibody

Clonality	monoclonal
Host	Mouse
Specificity	Human, Mouse, Rat
Tested Application	ELISA, WB, IHC, IF
Delivery Time	2 to 4 working days
Clone ID	4A9
Isotype	IgG1
Form	liquid
Purification	protein A+G purified
Purity	≥95% as determined by SDS-PAGE
Uniprot ID	P09874
Gene ID
Calculated MW	115 kDa, 89 kDa
Ссылка на страницу на сайте производителя	ссылка
Инструкция	PDF
Storage	0.01MPBS pH 7.4,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Background	PARP1 (poly(ADP-ribose) polymerase 1) is a nuclear enzyme catalyzing the poly(ADP-ribosyl)ation of many key proteins in vivo. The normal function of PARP1 is the routine repair of DNA damage. Activated by DNA strand breaks, the PARP1 is cleaved into an 85 to 89-kDa COOH-terminal fragment and a 24-kDa NH2-terminal peptide by caspases during the apoptotic process. The appearance of PARP fragments is commonly considered as an important biomarker of apoptosis.
Immunogen	poly (ADP-ribose) polymerase 1
Synonyms	ADPRT, ADPRT 1, ADPRT1, pADPRT 1, PARP, PARP 1, PARP1, poly (ADP ribose) polymerase 1, Poly [ADP ribose] polymerase 1, Poly[ADP ribose] synthase 1, PPOL
Recommended dilution	WB: 1:5000 - 1:30000; IHC: 1:100 - 1:1000; IF: 1:50 - 1:500
Immunohistochemistry of paraffin-embedded human breast cancer using FNab09939(PARP1 antibody) at dilution of 1:600
HeLa cells were subjected to SDS PAGE followed by western blot with FNab09939(PARP1 Antibody) at dilution of 1:20000

Область использования: Моноклональные антитела	Производство:	Fine Biotech
	Метод:	Антитела
	Объем:	100µg
	Кат. номер:	FNab09939
Цена (с НДС 20%):	по запросу	В корзину
Наименование: anti- PARP1 antibody. Примечание: