anti- OSBP antibody

Clonality	polyclonal
Host	Rabbit
Specificity	Human, Mouse, Rat
Tested Application	ELISA, WB, IHC, IP
Delivery Time	2 to 4 working days
Isotype	IgG
Form	liquid
Purification	Immunogen affinity purified
Purity	≥95% as determined by SDS-PAGE
Uniprot ID	P22059
Gene ID
Calculated MW	89 kDa
Ссылка на страницу на сайте производителя	ссылка
Инструкция	PDF
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Background	Lipid transporter involved in lipid countertransport between the Golgi complex and membranes of the endoplasmic reticulum: specifically exchanges sterol with phosphatidylinositol 4-phosphate(PI4P), delivering sterol to the Golgi in exchange for PI4P, which is degraded by the SAC1/SACM1L phosphatase in the endoplasmic reticulum(PubMed:24209621). Binds cholesterol and a range of oxysterols including 25-hydroxycholesterol(PubMed:15746430, PubMed:17428193). Cholesterol binding promotes the formation of a complex with PP2A and a tyrosine phosphatase which dephosphorylates ERK1/2, whereas 25-hydroxycholesterol causes its disassembly(PubMed:15746430). Regulates cholesterol efflux by decreasing ABCA1 stability(PubMed:18450749).
Immunogen	oxysterol binding protein
Synonyms	OSBP1
Immunohistochemistry of paraffin-embedded human ovary tumor using FNab06016(OSBP antibody) at dilution of 1:50

Область использования: Поликлональные антитела	Производство:	Fine Biotech
	Метод:	Антитела
	Объем:	100µg
	Кат. номер:	FNab06016
Цена (с НДС 20%):	по запросу	В корзину
Наименование: anti- OSBP antibody. Примечание: