| Clonality | monoclonal |
| Host | Mouse |
| Specificity | Human |
| Tested Application | ELISA, WB,IHC |
| Delivery Time | 2 to 4 working days |
| Clone ID | 8C0 |
| Isotype | IgG1 |
| Form | liquid |
| Purification | Protein A+G purification |
| Purity | ≥95% as determined by SDS-PAGE |
| Uniprot ID | Q96D31 |
| Gene ID | |
| Calculated MW | 32 kDa |
| Ссылка на страницу на сайте производителя | ссылка |
| Инструкция | PDF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| Background | Ca(2+) release-activated Ca(2+)(CRAC) channel subunit which mediates Ca(2+) influx following depletion of intracellular Ca(2+) stores and channel activation by the Ca(2+) sensor, STIM1. CRAC channels are the main pathway for Ca(2+) influx in T-cells and promote the immune response to pathogens by activating the transcription factor NFAT(PubMed:16582901). |
| Immunogen | ORAI calcium release-activated calcium modulator 1 |
| Synonyms | CRACM1, FLJ14466, ORAI1, ORAI1 L1, ORAI1 L2, Orail L2, ORAT1, Protein orai 1, TMEM142A, Transmembrane protein 142A |
| Recommended dilution | WB: 1:500-1:2000; IHC: 1:50-1:500 |
Immunohistochemistry of paraffin-embedded human lung cancer tissue slide using FNab06002(ORAI1 Antibody) at dilution of 1:200
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HL-60 cells were subjected to SDS PAGE followed by western blot with FNab06002(ORAI1 Antibody) at dilution of 1:1000
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