| Clonality | monoclonal |
| Host | Mouse |
| Specificity | Human, Mouse |
| Tested Application | ELISA, IHC, WB,IF |
| Delivery Time | 2 to 4 working days |
| Clone ID | 7C8 |
| Isotype | IgG2a |
| Form | liquid |
| Purification | Protein A+G purification |
| Purity | ≥95% as determined by SDS-PAGE |
| Uniprot ID | Q9UMX5 |
| Gene ID | |
| Calculated MW | 18 kDa |
| Ссылка на страницу на сайте производителя | ссылка |
| Инструкция | PDF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| Background | Acts as a neurotrophic factor in postnatal mature neurons enhancing neuronal survival. Promotes cell proliferation and neurogenesis in undifferentiated neural pro-genitor cells at the embryonic stage and inhibits differentiation of astrocyte. Its neurotrophic activity is exerted via MAPK1/ERK2, MAPK3/ERK1 and AKT1/AKT pathways. Neurotrophic activity is enhanced by binding to heme. Acts also as an anorexigenic neurotrophic factor that contributes to energy balance(By similarity). Plays a role in the human tumorigenesis(PubMed:22748190). |
| Immunogen | neuron derived neurotrophic factor |
| Synonyms | CIR2, NENF, NEUDESIN, SCIRP10, SPUF, SPUF protein |
| Recommended dilution | WB: 1:500-1:5000; IHC: 1:20-1:200; IF: 1:50-1:500 |
Immunohistochemistry of paraffin-embedded human kidney slide using FNab05661(NENF antibody) at dilution of 1:50
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human brain tissue were subjected to SDS PAGE followed by western blot with FNab05661(NENF antibody) at dilution of 1:1000
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