anti- MECP2 antibody

Спецификация

Clonality	polyclonal
Host	Rabbit
Specificity	Human, Mouse
Tested Application	ELISA, IHC, WB
Delivery Time	2 to 4 working days
Isotype	IgG
Form	liquid
Purification	Immunogen affinity purified
Purity	≥95% as determined by SDS-PAGE
Uniprot ID	P51608
Gene ID
Calculated MW	83 kDa
Ссылка на страницу на сайте производителя	ссылка
Инструкция	PDF
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background	DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation. MECP2 is dispensible in stem cells, but is essential for embryonic development. MECP2 gene mutations are the cause of most cases of Rett syndrome, a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females. Alternative splicing results in multiple transcript variants encoding different isoforms.
Immunogen	methyl CpG binding protein 2 (Rett syndrome)
Synonyms	AUTSX3
Recommended dilution	WB: 1:500 - 1:1000; IHC: 1:50 - 1:100
Immunohistochemistry of paraffin-embedded human gastric cancer using FNab05082(MECP2 antibody) at dilution of 1:50
MDA-MB-453s cells were subjected to SDS PAGE followed by western blot with FNab05082(MECP2 Antibody) at dilution of 1:1000

Информация для заказа

Область использования: Поликлональные антитела	Производство:	Fine Biotech
	Метод:	Антитела
	Объем:	100µg
	Кат. номер:	FNab05082
Цена (с НДС 20%):	по запросу	В корзину
Наименование: anti- MECP2 antibody. Примечание: