| Clonality | polyclonal |
| Host | Rabbit |
| Specificity | Human, Mouse |
| Tested Application | ELISA, WB, IHC, IP |
| Delivery Time | 2 to 4 working days |
| Isotype | IgG |
| Form | liquid |
| Purification | Immunogen affinity purified |
| Purity | ≥95% as determined by SDS-PAGE |
| Uniprot ID | P50135 |
| Gene ID | |
| Calculated MW | 27 kDa |
| Ссылка на страницу на сайте производителя | ссылка |
| Инструкция | PDF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
| Background | In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene. |
| Immunogen | histamine N-methyltransferase |
| Synonyms | HMT |
| Recommended dilution | WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IP : 1:20 - 1:50 |
Immunohistochemistry of paraffin-embedded mouse heart using FNab03944(HNMT antibody) at dilution of 1:50
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human liver tissue were subjected to SDS PAGE followed by western blot with FNab03944(HNMT antibody) at dilution of 1:1000
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