| Clonality | polyclonal |
| Host | Rabbit |
| Specificity | Mouse, Rat |
| Tested Application | ELISA, IHC, WB |
| Delivery Time | 2 to 4 working days |
| Isotype | IgG |
| Form | liquid |
| Purification | Immunogen affinity purified |
| Purity | ≥95% as determined by SDS-PAGE |
| Uniprot ID | Q15303 |
| Gene ID | |
| Calculated MW | 180 kDa |
| Ссылка на страницу на сайте производителя | ссылка |
| Инструкция | PDF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
| Background | This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. |
| Immunogen | v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) |
| Synonyms | HER4 |
| Recommended dilution | WB: 1:500 - 1:1000; IHC: 1:50 - 1:100 |
Immunohistochemistry of paraffin-embedded rat lung using FNab02829(ERBB4 antibody) at dilution of 1:100
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mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab02829(ERBB4 antibody) at dilution of 1:1000
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