| Clonality | polyclonal |
| Host | Rabbit |
| Specificity | Human, Mouse, Rat |
| Tested Application | ELISA, WB, IP |
| Delivery Time | 2 to 4 working days |
| Isotype | IgG |
| Form | liquid |
| Purification | Immunogen affinity purified |
| Purity | ≥95% as determined by SDS-PAGE |
| Uniprot ID | Q96N67 |
| Gene ID | |
| Calculated MW | 240 kDa |
| Ссылка на страницу на сайте производителя | ссылка |
| Инструкция | PDF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| Background | Functions as a guanine nucleotide exchange factor(GEF), which activates Rac1 and Rac3 Rho small GTPases by exchanging bound GDP for free GTP. Does not have a GEF activity for CDC42. Required for STMN1 'Ser-15' phosphorylation during axon formation and consequently for neuronal polarization(PubMed:16982419). Has a role in pigmentation(By similarity). Involved in the regulation of cortical neurogenesis through the control of radial glial cells(RGCs) proliferation versus differentiation; negatively regulates the basal-to-apical interkinetic nuclear migration of RGCs by antagonizing the microtubule growth-promoting function of TACC3(By similarity).Multiple isoforms of DOCK 7 exist due to alternative splicing events. This DOCK 7 antibody can recognize all the isoforms. |
| Immunogen | dedicator of cytokinesis 7 |
| Synonyms | dedicator of cytokinesis 7, DOCK7, KIAA1771, ZIR2 |
| Recommended dilution | WB: 1:200-1:1000; IP: 1:500-1:1000 |
mosue brain tissue were subjected to SDS PAGE followed by western blot with FNab02497(DOCK7 antibody) at dilution of 1:400
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Наименование: anti- DOCK7 antibody.