| Clonality | polyclonal |
| Host | Rabbit |
| Specificity | Human |
| Tested Application | ELISA |
| Delivery Time | 2 to 4 working days |
| Isotype | IgG |
| Form | liquid |
| Purification | Immunogen affinity purified |
| Purity | ≥95% as determined by SDS-PAGE |
| Uniprot ID | Q99829 |
| Gene ID | |
| Ссылка на страницу на сайте производителя | ссылка |
| Инструкция | PDF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| Background | Calcium-dependent phospholipid-binding protein that plays a role in calcium-mediated intracellular processes(PubMed:14674885). Involved in the TNF-alpha receptor signaling pathway in a calcium-dependent manner(PubMed:14674885). Exhibits calcium-dependent phospholipid binding properties(PubMed:9430674, PubMed:19539605). Plays a role in neuronal progenitor cell differentiation; induces neurite outgrowth via a AKT-dependent signaling cascade and calcium-independent manner(PubMed:23263657, PubMed:25450385). May recruit target proteins to the cell membrane in a calcium-dependent manner(PubMed:12522145). May function in membrane trafficking(PubMed:9430674). Involved in TNF-alpha-induced NF-kappa-B transcriptional repression by inducing endoprotease processing of the transcription factor NF-kappa-B p65/RELA subunit(PubMed:18212740). Also induces endoprotease processing of NF-kappa-B p50/NFKB1, p52/NFKB2, RELB and REL(PubMed:18212740). |
| Immunogen | copine I |
| Synonyms | CPN1 |
| | |