| Clonality | polyclonal |
| Host | Rabbit |
| Specificity | Human |
| Tested Application | ELISA, WB, IP |
| Delivery Time | 2 to 4 working days |
| Isotype | IgG |
| Form | liquid |
| Purification | Immunogen affinity purified |
| Purity | ≥95% as determined by SDS-PAGE |
| Uniprot ID | P28715 |
| Calculated MW | 133 kDa, Observed 200 kDa |
| Ссылка на страницу на сайте производителя | ссылка |
| Инструкция | PDF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| Background | The human genes correcting DNA repair defects are termed excision-repair cross-complementing or ERCC genes. The ERCC5 gene corrects the excision repair deficiency of Chinese hamster ovary cell line UV135 of complementation group 5. The human ERCC5 gene product is a structure-specific endonuclease required for making the 3-prime incision during DNA nucleotide excision-repair(NER). It also plays an important role in regulating DNA excision repair, removal of bulky lesions caused by environmental chemicals or UV light [PMID:22815677]. |
| Immunogen | excision repair cross-complementing rodent repair deficiency, complementation group 5 |
| Synonyms | COFS3, ERCC5, ERCM2, UVDR, XPG, XPGC |
| Recommended dilution | WB: 1:200-1:2000; IF: 1:20-1:200; IP: 1:200-1:2000 |
HeLa cells were subjected to SDS PAGE followed by western blot with FNab09547(ERCC5 antibody) at dilution of 1:500
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Наименование: anti- XPG antibody.