| Clonality | polyclonal |
| Host | Rabbit |
| Specificity | Human, Mouse, Rat |
| Tested Application | ELISA, WB, IF, FC |
| Delivery Time | 2 to 4 working days |
| Isotype | IgG |
| Form | liquid |
| Purification | Immunogen affinity purified |
| Purity | ≥95% as determined by SDS-PAGE |
| Uniprot ID | P54578 |
| Gene ID | |
| Calculated MW | 97 kDa |
| Ссылка на страницу на сайте производителя | ссылка |
| Инструкция | PDF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| Background | Proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. Ensures the regeneration of ubiquitin at the proteasome. Is a reversibly associated subunit of the proteasome and a large fraction of proteasome-free protein exists within the cell. Required for the degradation of the chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis. Serves also as a physiological inhibitor of endoplasmic reticulum-associated degradation(ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1. Indispensable for synaptic development and function at neuromuscular junctions(NMJs). |
| Immunogen | ubiquitin specific peptidase 14(tRNA-guanine transglycosylase) |
| Synonyms | Deubiquitinating enzyme 14, TGT, Ubiquitin thiolesterase 14, USP14 |
| Recommended dilution | WB: 1:500-1:5000; IP: 1:500-1:5000; IF: 1:10-1:100 |
mouse kidney tissue were subjected to SDS PAGE followed by western blot with FNab09310(USP14 antibody) at dilution of 1:300
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Наименование: anti- USP14 antibody.