anti-GPI antibodyСпецификация| Highlight | New Arrivals -2022 | | Clonality | monoclonal | | Host | Mouse | | Specificity | Human | | Tested Application | ELISA, WB, IHC, IF | | Delivery Time | 2 to 4 working days | | Isotype | IgG1 | | Form | liquid | | Purification | Protein A+G purification | | Purity | ≥95% as determined by SDS-PAGE | | Uniprot ID | P06744 | | Calculated MW | 55-64 kDa | | Ссылка на страницу на сайте производителя | ссылка | | Инструкция | PDF | | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) | | Background | This gene encodes a member of the glucose phosphate isomerase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. In the cytoplasm, the gene product functions as a glycolytic enzyme (glucose-6-phosphate isomerase) that interconverts glucose-6-phosphate and fructose-6-phosphate. Extracellularly, the encoded protein (also referred to as neuroleukin) functions as a neurotrophic factor that promotes survival of skeletal motor neurons and sensory neurons, and as a lymphokine that induces immunoglobulin secretion. The encoded protein is also referred to as autocrine motility factor based on an additional function as a tumor-secreted cytokine and angiogenic factor. Defects in this gene are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment. Alternative splicing results in multiple transcript variants. | | Immunogen | Glucose-6-phosphate isomerase | | Synonyms | GPI, AMF, GNPI, NLK, PGI | | Recommended dilution | WB: 1:2000-1:20000; IHC: 1:200-1:1000; IF: 1:50-1:200 | | | |
Информация для заказа| Область использования: | Производство: | Fine Biotech | | Метод: | Антитела | | Объем: | 100µg | | Кат. номер: | FNab10496 | | Цена (с НДС 20%): | по запросу | В корзину  |  Наименование: anti-GPI antibody.
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