Антитела anti- NT5E/CD73 antibodyanti- NT5E/CD73 antibodyСпецификация| Clonality | polyclonal | | Host | Rabbit | | Specificity | Human, Mouse, Rat | | Tested Application | ELISA, WB,IHC,FC | | Delivery Time | 2 to 4 working days | | Isotype | IgG | | Form | liquid | | Purification | Immunogen affinity purified | | Purity | ≥95% as determined by SDS-PAGE | | Uniprot ID | P21589 | | Calculated MW | 63 kDa | | Ссылка на страницу на сайте производителя | ссылка | | Инструкция | PDF | | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) | | Background | NT5E(5'-nucleotidase) is also named as NT5, NTE,CD73,ecto-5'-nucleotidase, and belongs to the 5'-nucleotidase family. It catalyzes the conversion at neutral pH of purine 5-prime mononucleotides to nucleosides, the preferred substrate being AMP.The enzyme occurs mainly as a dimer and the wide distribution of NT5E in the rat hippocampus, suggesting their involvement in the control of the purinergic signaling(PMID:17619139). This protein has two isoforms with the molecular weight of 63 kDa and 58 kDa and four glycosylation sites with a signalpeptide. It can exsit as a dimer(PMID:17619139). It can be detected the band of 55 kDa,64 kDa, 70 kDa, 110 kDa by western blot(PMID:17619139; 12370277; 21533188). Defects in NT5E are the cause of calcification of joints and arteries(CALJA). | | Immunogen | 5'-nucleotidase, ecto(CD73) | | Synonyms | 5 NT, 5 nucleotidase, 5' nucleotidase, ecto(CD73), CD73, E5NT, Ecto 5 nucleotidase, eN, eNT, NT, NT5, NT5E, NTE | | Recommended dilution | WB: 1:500-1:5000; IHC: 1:50-1:500 | Immunohistochemistry of paraffin-embedded human stomach cancer tissue slide using FNab05878(NT5E,CD73 Antibody) at dilution of 1:200
 | Jurkat cells were subjected to SDS PAGE followed by western blot with FNab05878(NT5E,CD73 antibody) at dilution of 1:1000
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Информация для заказа| Область использования: | Производство: | Fine Biotech | | Метод: | Антитела | | Объем: | 100µg | | Кат. номер: | FNab05878 | | Цена (с НДС 20%): | по запросу | В корзину  | Наименование: Антитела anti- NT5E/CD73 antibody / anti- NT5E/CD73 antibody.
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