anti- uPA antibodyСпецификация| Clonality | polyclonal | | Host | Rabbit | | Specificity | Human, Mouse, Rat | | Tested Application | ELISA, WB, IHC, IP, IF | | Delivery Time | 2 to 4 working days | | Isotype | IgG | | Form | liquid | | Purification | Immunogen affinity purified | | Purity | ≥95% as determined by SDS-PAGE | | Uniprot ID | P00749 | | Gene ID | | | Calculated MW | 50 kDa | | Ссылка на страницу на сайте производителя | ссылка | | Инструкция | PDF | | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) | | Background | PLAU(Urokinase-type plasminogen activator) is also named as uPA and belongs to the peptidase S1 family.UPA initiates a proteolytic cascade, which degrades extracellular matrix during tissue growth and remodelling.The secreted proform of UPA is activated after binding to a specific high affinity cell surface receptor. Secreted UPA is exposed to rapid inactivation in the pericellular space by plasminogen activator inhibitor-1(PAI-1), which is stored in the extracellular matrix bound to vitronectin(PMID:9665342).It has 2 isoforms produced by alternative splicing.Defects in PLAU are the cause of Quebec platelet disorder(QPD). | | Immunogen | plasminogen activator, urokinase | | Synonyms | ATF, PLAU, U plasminogen activator, uPA, URK | | Recommended dilution | WB: 1:500-1:1000; IHC：1:20-1:200；IF: 1：20-1：200; IP: 1：500-1：2000 | Immunohistochemistry of paraffin-embedded human skin using FNab09267(uPA antibody) at dilution of 1:50
 | HeLa cells were subjected to SDS PAGE followed by western blot with FNab09267(uPA antibody) at dilution of 1:500
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Информация для заказа| Область использования: | Производство: | Fine Biotech | | Метод: | Антитела | | Объем: | 100µg | | Кат. номер: | FNab09267 | | Цена (с НДС 20%): | по запросу | В корзину  | Наименование: anti- uPA antibody.
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