| Clonality | polyclonal |
| Host | Rabbit |
| Specificity | Human, Rat |
| Tested Application | ELISA, WB,IHC |
| Delivery Time | 2 to 4 working days |
| Isotype | IgG |
| Form | liquid |
| Purification | Immunogen affinity purified |
| Purity | ≥95% as determined by SDS-PAGE |
| Uniprot ID | O75385 |
| Gene ID | |
| Calculated MW | 150 kDa |
| Ссылка на страницу на сайте производителя | ссылка |
| Инструкция | PDF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| Background | ULK1, also named as KIAA0722, belongs to the protein kinase superfamily, Ser/Thr protein kinase family and APG1/unc-51/ULK1 subfamily. It is involved in autophagy. ULK1 is required for autophagosome formation. It forms a stable complex with Atg13 and focal adhesion kinase(FAK) family interacting protein of 200 kDa(FIP 200)(PMID:21460634). ULK1 phosphorylates ATG13/KIAA0652. It is involved in axon growth. ULK1 plays an essential role in neurite extension of cerebellar granule cells. ULK1 represents a potential novel prognostic biomarker for HCC patients and may play an important role during the progression of HCC(PMID:23573318). |
| Immunogen | unc-51-like kinase 1(C. elegans) |
| Synonyms | ATG1, FLJ38455, FLJ46475, KIAA0722, ULK1, Unc 51 like kinase 1, UNC51, Unc51.1 |
| Recommended dilution | WB: 1:200-1:1000; IHC: 1：50-1：500 |
Immunohistochemistry of paraffin-embedded human skeletal muscle tissue slide using FNab09251(ULK1 Antibody) at dilution of 1:200
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rat skeletal muscle tissue were subjected to SDS PAGE followed by western blot with FNab09251(ULK1 Antibody) at dilution of 1:300
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