| Clonality | polyclonal |
| Host | Rabbit |
| Specificity | Human, Mouse |
| Tested Application | ELISA, WB |
| Delivery Time | 2 to 4 working days |
| Isotype | IgG |
| Form | liquid |
| Purification | Immunogen affinity purified |
| Purity | ≥95% as determined by SDS-PAGE |
| Uniprot ID | Q9UPW8 |
| Calculated MW | 27 kDa |
| Ссылка на страницу на сайте производителя | ссылка |
| Инструкция | PDF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| Background | UNC13A, also named as KIAA1032, belongs to the unc-13 family. It plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. UNC13A is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity-dependent refilling of readily releasable vesicle pool(RRP). It is essential for synaptic vesicle maturation in most excitatory/glutamatergic but not inhibitory/GABA-mediated synapses. UNC13A is also involved in secretory granule priming in insulin secretion. The antibody is specific to UNC13A. |
| Immunogen | unc-13 homolog A(C. elegans) |
| Synonyms | KIAA1032, Munc13 1, Protein unc 13 homolog A, unc 13 homolog A(C. elegans), UNC13A |
| Recommended dilution | WB: 1:500-1:5000; IP: 1：200-1：2000 |
human brain tissue were subjected to SDS PAGE followed by western blot with FNab09255(UNC13A antibody) at dilution of 1:300
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Наименование: anti- UNC13A/Munc13-1 antibody.