anti- TP63 antibody

Clonality	monoclonal
Host	Mouse
Specificity	Human
Tested Application	ELISA, WB
Delivery Time	2 to 4 working days
Clone ID	2A3
Isotype	IgG1
Form	liquid
Purification	Protein A+G purification
Purity	≥95% as determined by SDS-PAGE
Uniprot ID	Q9H3D4
Gene ID
Ссылка на страницу на сайте производителя	ссылка
Инструкция	PDF
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Background	Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. Isoform 2 activates RIPK4 transcription. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. Involved in Notch signaling by probably inducing JAG1 and JAG2. Plays a role in the regulation of epithelial morphogenesis. The ratio of DeltaN-type and TA*-type isoforms may govern the maintenance of epithelial stem cell compartments and regulate the initiation of epithelial stratification from the undifferentiated embryonal ectoderm. Required for limb formation from the apical ectodermal ridge. Activates transcription of the p21 promoter.
Immunogen	tumor protein p63
Synonyms	KET, P63, P73H, P73L, TP73L
WB Image

Область использования: Моноклональные антитела	Производство:	Fine Biotech
	Метод:	Антитела
	Объем:	100µg
	Кат. номер:	FNab08880
Цена (с НДС 20%):	по запросу	В корзину
Наименование: anti- TP63 antibody. Примечание: