| Clonality | polyclonal |
| Host | Rabbit |
| Specificity | Human, Mouse, Rat |
| Tested Application | ELISA, WB |
| Delivery Time | 2 to 4 working days |
| Isotype | IgG |
| Form | liquid |
| Purification | Immunogen affinity purified |
| Purity | ≥95% as determined by SDS-PAGE |
| Uniprot ID | Q86T82 |
| Gene ID | |
| Calculated MW | 123 kDa |
| Ссылка на страницу на сайте производителя | ссылка |
| Инструкция | PDF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| Background | Deubiquitinase that antagonizes the anaphase-promoting complex(APC/C) during G1/S transition by mediating deubiquitination of cyclin-A(CCNA1 and CCNA2), thereby promoting S phase entry. Specifically mediates deubiquitination of 'Lys-11'-linked polyubiquitin chains, a specific ubiquitin-linkage type mediated by the APC/C complex. Also mediates deubiquitination of 'Lys-48'-linked polyubiquitin chains in vitro. Phosphorylation at Ser-628 during G1/S phase maximizes the deubiquitinase activity, leading to prevent degradation of cyclin-A(CCNA1 and CCNA2). |
| Immunogen | ubiquitin specific peptidase 37 |
| Synonyms | Deubiquitinating enzyme 37, KIAA1594, Ubiquitin thiolesterase 37, USP37 |
| Recommended dilution | WB: 1:500-1:5000; IP: 1：200-1：2000 |
HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab09330(USP37 antibody) at dilution of 1:500
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Наименование: anti- USP37 antibody.