| Clonality | polyclonal |
| Host | Rabbit |
| Specificity | Human |
| Tested Application | ELISA, WB, IHC |
| Delivery Time | 2 to 4 working days |
| Isotype | IgG |
| Form | liquid |
| Purification | Immunogen affinity purified |
| Purity | ≥95% as determined by SDS-PAGE |
| Uniprot ID | P41220 |
| Gene ID | |
| Calculated MW | 24kd |
| Ссылка на страницу на сайте производителя | ссылка |
| Инструкция | PDF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| Background | Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form(PubMed:11063746, PubMed:19478087). Plays a role in the regulation of blood pressure in response to signaling via G protein-coupled receptors and GNAQ. Plays a role in regulating the constriction and relaxation of vascular smooth muscle(By similarity). Binds EIF2B5 and blocks its activity, thereby inhibiting the translation of mRNA into protein(PubMed:19736320). |
| Immunogen | regulator of G-protein signaling 2, 24kDa |
| Synonyms | G0S8, RGS2 |
| Recommended dilution | WB: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:50-1:500 |
Immunohistochemistry of paraffin-embedded human pancreas cancer using FNab07269(RGS2 antibody) at dilution of 1:50
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fetal human brain tissue were subjected to SDS PAGE followed by western blot with FNab07269(RGS2 Antibody) at dilution of 1:500
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