| Clonality | polyclonal |
| Host | Rabbit |
| Specificity | Human, Rat |
| Tested Application | ELISA, WB, IHC, IF |
| Delivery Time | 2 to 4 working days |
| Isotype | IgG |
| Form | liquid |
| Purification | Immunogen affinity purified |
| Purity | ≥95% as determined by SDS-PAGE |
| Uniprot ID | Q8IXJ6 |
| Gene ID | |
| Calculated MW | Refer to Figures |
| Ссылка на страницу на сайте производителя | ссылка |
| Инструкция | PDF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
| Background | This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Several transcript variants are resulted from alternative splicing of this gene. |
| Immunogen | sirtuin (silent mating type information regulation 2 homolog) 2 |
| Synonyms | SIR2L, SIR2L2 |
| Recommended dilution | WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:10 - 1:100 |
Immunohistochemistry of paraffin-embedded human lung cancer tissue slide using FNab07879( SIRT2 Antibody) at dilution of 1:100
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mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab07879(SIRT2 antibody) at dilution of 1:1000
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